for people ages 55 years and up (full criteria)
at La Jolla, California and other locations
study started
estimated completion:



This study will assess the safety and efficacy of the brimonidine intravitreal implant in patients with geographic atrophy due to age-related macular degeneration.


Geographic Atrophy Macular Degeneration Atrophy Brimonidine Tartrate 400 µg Brimonidine Implant Sham


You can join if…

Open to people ages 55 years and up

  • Geographic atrophy due to age-related macular degeneration in the study eye
  • Visual acuity better than or equal to 20/125 in the study eye and 20/200 in the fellow eye

You CAN'T join if...

  • Cataract surgery or Laser-Assisted in situ Keratomileusis (LASIK) in the study eye in the last 3 months
  • Infections in either eye in the last 3 months


  • University of California, San Diego, Jacobs Retina Center, Shiley Eye Center
    La Jolla, California, 92093, United States
  • Retinal Consultants of Arizona, Ltd., Retinal Research Institute
    Phoenix, Arizona, 85014, United States
  • Associated Retina Consultants
    Phoenix, Arizona, 85020, United States
  • Northern California Retina Vitreous Associates
    Mountain View, California, 94040, United States
  • Retina Consultants of Southern Colorado, PC
    Colorado Springs, Colorado, 80909, United States
  • Oregon Retina, LLP
    Eugene, Oregon, 97401, United States
  • Casey Eye Institute, Oregon Health and Science University
    Portland, Oregon, 97239, United States
  • Retina Research Institute of Texas
    Abilene, Texas, 79606, United States
  • Strategic Clinical Research Group, LLC
    Willow Park, Texas, 76087, United States
  • "Austin Retina Associates "
    Austin, Texas, 78705, United States
  • Texas Retina Associates
    Arlington, Texas, 76012, United States
  • Retina Foundation of the Southwest
    Dallas, Texas, 75231, United States
  • Valley Retina Institute
    McAllen, Texas, 78503, United States
  • Retina Specialty Institute
    Pensacola, Florida, 32503, United States
  • Raj K. Maturi, MD
    Indianapolis, Indiana, 46290, United States
  • Georgia Retina
    Decatur, Georgia, 30030, United States
  • Southern Vitreoretinal Associates, PL
    Tallahassee, Florida, 32308, United States
  • Charlotte Eye Ear Nose & Throat Associates, PA
    Charlotte, North Carolina, 28210, United States
  • Retina Vitreous Associates of Florida
    Saint Petersburg, Florida, 33711, United States
  • Center for Retina and Macular Disease
    Winter Haven, Florida, 33880, United States
  • "National Ophthalmic Research Institute Retina Consultants of Southwest Florida"
    Fort Myers, Florida, 33912, United States
  • Retina Associates of Western New York
    Rochester, New York, 14620, United States
  • Mid Atlantic Retina, Wills Eye Retina Surgeons
    Philadelphia, Pennsylvania, 19107, United States
  • Macular Unit, Hospital of St Cross
    Bristol, BS1 2LX, United Kingdom
  • Moorfields Eye Hospital
    London, EC1V 2PD, United Kingdom
  • Macular Unit, Hospital of St Cross
    Rugby, CV22 5PX, United Kingdom
  • Royal Hallamshire Hospital, Eye Department
    Sheffield, S10 2JF, United Kingdom
  • Frimley Park Hospital, Eye clinical trials Unit, Department of Opthalmology
    Surrey, GU16 7UJ, United Kingdom
  • Service d'Ophtalmologie
    Bordeaux, 33076, France
  • "Centre Hospitalier Intercommunal de Creteil "
    Creteil, 94000, France
  • "Universitat Bonn, Abteilung fur Augenheilkunde "
    Bonn, 53127, Germany
  • STZ Eyetrial
    Tübingen, 72076, Germany
  • Università di Cagliari (presidio San Giovanni di Dio)
    Bologna, 40138, Italy
  • Università di Cagliari (presidio San Giovanni di Dio)
    Cagliari, 09124, Italy
  • Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico
    Milano, 20122, Italy
  • IRCCS Ospedale San Raffaele
    Milano, 20132, Italy
  • "Dir IV Clinica Oculistica di Milano, Ospedale Generale ""Luigi Sacco"" "
    Milano, 20157, Italy
  • Universita degli Studi di Padova, Dipartimento di Neuroscienze
    Padova, 35128, Italy
  • Universita degli Studi di Torino
    Torino, 10122, Italy
  • Center for Eye Research Australia
    Melbourne, Victoria, 3002, Australia
  • Lions Eye Institute, University of Western Australia
    Nedlands, 6009, Australia


in progress, not accepting new patients
Start Date
Completion Date
More Information
Phase 2
Study Type
Last Updated
July 20, 2017