HIV-Associated Dementia clinical trials at UCSD
4 in progress, 2 open to eligible people
LATITUDE Study: Long-Acting Therapy to Improve Treatment SUccess in Daily LifE
open to eligible people ages 18 years and up
The purpose of this study is to compare the efficacy, safety, and durability of two different strategies to treat participants with a history of sub-optimal adherence and control of their HIV infection: long-acting (LA) antiretroviral therapy (ART) and all-oral standard of care (SOC).
San Diego, California and other locations
Very Early Intensive Treatment of HIV-Infected Infants to Achieve HIV Remission
open to all eligible people
The study will explore the effects of early intensive antiretroviral therapy (ART) on achieving HIV remission (HIV RNA below the limit of detection of the assay) among HIV-infected infants.
La Jolla, California and other locations
Digital Health Feedback System for Longitudinal Measurement of Medication Adherence During Anti-Retroviral (ARV)Therapy
Sorry, in progress, not accepting new patients
This study uses an ingestion sensor and a wearable sensor (worn as a patch on the skin), which are new Proteus Digital Health (PDH) technologies approved by the FDA, to collect information about patients taking their ARV medications. The wearable sensor records information, which is uploaded wirelessly to a mobile device and then to a secure computer. Together the sensors and the mobile device transmitting the information to the study computer are called a digital health feedback system (DHFS), which gives healthcare providers information about when patients have taken their ARV medications. The purpose of the study is to demonstrate that the DHFS is easy to use and acceptable to the HIV patient population; that patients will persist with its use; and that the system provides valid, accurate measures of adherence.
San Diego, California and other locations
Tesamorelin for Cognition in Aging HIV-Infected Persons
Sorry, in progress, not accepting new patients
The aim of this study is to test whether tesamorelin, in combination with a text-messaging application to help with motivation and adherence, will significantly improve memory and thinking in HIV.
San Diego, California and other locations
Our lead scientists for HIV-Associated Dementia research studies include Ronald J Ellis, MD, PhD Sara H Browne, MD, MPH Constance A Benson, MD.