Clinical Trials Open to Healthy Volunteers

A “healthy volunteer” is someone who doesn't have any major health problems, and takes part in research to test new medicines, devices, or treatments. UCSD offers clinical trials on a wide range of medical conditions. Healthy volunteers can help UCSD researchers make better comparisons to better understand the treatment of diseases.

• Adolescent Master Protocol for Participants 18 Years of Age and Older (AMP Up)

  • study on HIV/AIDS and Immunodeficiency
  • open to healthy people ages 18 years and up

• Allergic Disease Onset Prevention Study

  • study on Atopic Dermatitis (Eczema) and Type 1 Hypersensitivity
  • open to healthy people

• Alzheimer's Disease Neuroimaging Initiative 3 (ADNI3) Protocol

  • study on Mild Cognitive Impairment and Alzheimer's Disease
  • open to healthy people ages 55-90

• AMP SCZ® Observational Study: PREDICT-DPACC

  • study on Clinical High Risk and Psychotic Disorders
  • open to healthy people ages 12-30

• ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

  • study on Frontotemporal Lobar Degeneration and Progressive Supranuclear Palsy
  • open to healthy people ages 18 years and up

• Association of Microbiome Patterns With Chronic Opioid Use

  • study on Pain and Opioid Use
  • open to healthy people ages 18 years and up

• Beta-Agonist Versus OnabotulinumtoxinA Trial for Urgency Urinary Incontinence

  • study on Urinary Incontinence
  • open to healthy females ages 18 years and up

• Brain Mechanisms Supporting Cannabis-induced Pain Relief

  • study on Pain and Cannabis
  • open to healthy people ages 21-65

• Cannabis Effects on Antiretroviral Therapy Pharmacokinetics and Neurotoxicity

  • study on HIV/AIDS and Cannabis
  • open to healthy people ages 18 years and up

• Cannabis on Cognition and Endocannabinoid Levels in Bipolar Disorder Patients and Healthy Volunteers

  • study on Bipolar Disorder and Cannabis
  • open to healthy people ages 18-50

• Cannabis Use, Cognition, and the Endocannabinoid System in HIV

  • study on HIV/AIDS and Cannabis
  • open to healthy people ages 18-65

• Clinical Feasibility of a Conformal Ultrasound Blood Pressure Sensor

  • study on Feasibility Study and Medical Device
  • open to healthy people ages 18-90

• Comparing Clinical Outcomes of Suture Button Versus Fibulink Fixation for Acute Ankle Syndesmosis Injuries

  • study on Ankle Injuries and Syndesmotic Injuries
  • open to healthy people ages 18 years and up

• Comparison of Prolonged Exposure Therapy, Pharmacotherapy, and Their Combination for PTSD

  • study on Post-Traumatic Stress Disorder
  • open to healthy people ages 18-75

• Consent for Use of Stored Patient Specimens for Future Testing

  • study on HIV/AIDS
  • open to healthy people

• Continuous Glucose Monitoring in Infants

  • study on Neonatal Hypoglycemia
  • open to healthy people

• CPAP for SDB in Patients Who Use Opioids

  • study on Sleep Disorders and Pain
  • open to healthy people ages 18 years and up

• Defecation Patterns in Constipated Patients

  • study on Constipation
  • open to healthy people ages 21-75

• Developing an EEG Paradigm to Study Prediction Error in Anorexia Nervosa

  • study on Anorexia
  • open to healthy females ages 11-17

• Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001

  • study on Alzheimer's Disease and Dementia
  • open to healthy people ages 18-80

• Dosimetry of Tc-99m-Tilmanocept

  • study on Diabetes and Kidney Disease
  • open to healthy people ages 18 years and up

• Dyadic Sleep Health Approach for Persons With Alzheimer's Disease and Caregivers

  • study on Sleep and Alzheimer's Disease
  • open to healthy people ages 18 years and up

• Effectiveness and Implementation of eScreening in Post 9/11 Transition Programs

  • study on Depression and Post-Traumatic Stress Disorder
  • open to healthy people ages 18 years and up

• Electrical Vestibular Nerve Stimulation (VeNS) as a Treatment for PTSD

  • study on Post-Traumatic Stress Disorder and Stress
  • open to healthy people ages 22-80

• Enhancing Capacity in Churches to Implement PA Programs

  • study on Cardiovascular Disease
  • open to healthy females ages 18-65

• Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

  • study on Huntington's Disease
  • open to healthy people ages 18 years and up

• Environmental and Reproductive Health Risk for Lewy Body Dementia

  • study on Dementia and Lewy Body Dementia
  • open to healthy people ages 18 years and up

• Family Functioning in Obesity Treatment for Mexican Americans

  • study on Obesity
  • open to healthy females ages 18-65

• Family, Responsibility, Education, Support, and Health for Families With a Child With Autism

  • study on Autism and Obesity
  • open to healthy people ages 6-12

• Food Aversion in Patients With Anorexia Nervosa

  • study on Anorexia
  • open to healthy females ages 18-55

• Healing Experiences of Adversity Among Latinos (HEALthy4You)

  • study on Mental Health and Stress
  • open to healthy people ages 5-11

• iKanEat: A Randomized-controlled, Multi-center Trial of Megestrol for Chronic Oral Food Refusal in Children

  • study on Feeding Behavior and Feeding Disorder of Infancy or Early Childhood
  • open to healthy people ages 9 months to 108 months

• Incentive Processing and Learning in Anorexia Nervosa and Bulimia Nervosa

  • study on Anorexia and Bulimia
  • open to healthy females ages 18-39

• Keep Contraceptive Arm Long Acting-iMplant (CALM) and Carry On

  • study on Contraception and Family Planning
  • open to healthy females ages 18-50

• Lenacapavir for HIV Pre-Exposure Prophylaxis in People Who Are at Risk for HIV Infection

  • study on HIV/AIDS and PrEP
  • open to healthy people ages 16 years and up

• Longitudinal Endotyping Of Atopic Dermatitis Through Transcriptomic Skin Analysis

  • study on Atopic Dermatitis (Eczema)
  • open to healthy people ages 6 years and up

• Longitudinal Performance of Epi proColon

  • study on Colorectal Cancer and Colorectal Tumor
  • open to healthy people ages 50-74

• Low-Dose Intravenous Ketamine for Adolescents With Depression and Suicidal Ideation in the Emergency Department

  • study on Depression and Suicidal Ideation
  • open to healthy people ages 12-18

• Mechanisms of Affective Touch in Chronic Pain

  • study on Fibromyalgia and Pain
  • open to healthy people ages 18-65

• Mediterranean Diet in Inflammatory Bowel Disease

  • study on Inflammatory Bowel Disease
  • open to healthy people ages 18 years and up

• Mobile Biosensor for Measuring Vital Signs in Healthcare and Home Settings

  • study on Pulse Oximetry
  • open to healthy people ages 13 years and up

• Mobile Web-based Behavioral Intervention for Improving Caregiver Well-being

  • study on Depression and Mental Health
  • open to healthy people ages 40 years and up

• Negative Affect in Individuals With Binge Eating Episodes

  • study on Bulimia and Binge Eating Disorder
  • open to healthy people ages 18-55

• No Post Intubation Laryngeal Symptoms

  • study on Sore-throat and Dysphonia
  • open to healthy people ages 18 years and up

• North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

  • study on Mitochondrial Disorders and Mitochondrial Genetic Disorders
  • open to healthy people

• Onboarding Positives and PrEP Users to Engage Negatives (OPPEN): Peer-driven Education to Link YMSM of Color to PrEP

  • study on HIV/AIDS and PrEP
  • open to healthy males ages 18-34

• OTIS Autoimmune Diseases in Pregnancy Project

  • study on Crohn's Disease and Inflammatory Bowel Disease
  • open to healthy females

• Pancreatic Cancer Early Detection Consortium

  • study on Pancreatic Cancer and Pancreatic Cyst
  • open to healthy people ages 18-90

• Patient-Centered Reproductive Decision Support Tool for Women Veterans

  • study on Contraception and Prepregnancy Health
  • open to healthy females ages 18-44

• PERsonalized Mood Augmentation Trial for Depressed Mood

  • study on Depression
  • open to healthy people ages 15 years and up

• Pharmacist Provision of Medication Abortion

  • study on Abortion
  • open to healthy females ages 18-50

• PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

  • study on Parkinson's Disease
  • open to healthy people ages 30 years and up

• Practice Facilitation as a Strategy to Improve Alcohol Treatment Adoption and Implementation in HIV Care

  • study on HIV/AIDS and Alcohol Use
  • open to healthy people ages 18 years and up

• Prematurity Risk Assessment Combined With Clinical Interventions for Improving Neonatal outcoMEs

  • study on Early Labor and Premature Birth
  • open to healthy females ages 18 years and up

• Project 2VIDA! COVID-19 Vaccine Intervention Delivery for Adults in Southern California

  • study on Vaccine and COVID-19
  • open to healthy people ages 16-99

• Race-Based Stress Trauma and Empowerment

  • study on Stress and Racism
  • open to healthy people ages 18 years and up

• Researchers at UC San Diego Are Learning About the Benefits of Human Milk and How it Influences Infant and Child Health

  • study on Breastfeeding and COVID-19
  • open to healthy females ages 18 years and up

• Retrograde Femoral Nail-Advanced Outcomes for Fixation of Distal Femur and Femoral Shaft Fractures

  • study on Femoral Fracture
  • open to healthy people ages 18 years and up

• Safety and Immunogenicity of a Single Dose of the Recombinant Live-Attenuated Respiratory Syncytial Virus (RSV) Vaccines RSV ΔNS2/Δ1313/I1314L, RSV 6120/ΔNS2/1030s, RSV 276 or Placebo, Delivered as Nose Drops to RSV-Seronegative Children 6 to 24 Months of Age

  • study on RSV and Vaccine
  • open to healthy people ages 6 months to 25 months

• Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-946 in Healthy Volunteers and in Participants With Sickle Cell Disease

  • study on Anemia and Sickle Cell Anemia
  • open to healthy people ages 18-70

• Statewide System and Organizational Strategy for EBP Implementation

  • open to healthy people ages 18 years and up

• StimRouter Registry Clinical Protocol

  • study on Pain and Neuropathy
  • open to healthy people ages 18 years and up

• Stress and Neurofeedback in Anorexia Nervosa

  • study on Anorexia
  • open to healthy people ages 18-45

• Surveillance Monitoring for ART Toxicities Study in HIV Uninfected Children Born to HIV Infected Women

  • study on Antiretroviral Toxicity
  • open to healthy people

• Taletrectinib Phase 2 Global Study in ROS1 Positive NSCLC

  • study on Lung Cancer and Non-Small Cell Lung Cancer
  • open to healthy people ages 18 years and up

• Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures

  • study on Amyotropic Lateral Sclerosis (ALS) and Movement Disorders
  • open to healthy people ages 18 years and up

• UCSD RELINK: Connecting Adults To Supportive Services

  • study on Health Care Utilization
  • open to healthy people ages 18 years and up

• Vagal Nerve Stimulation to Probe Inflammation and Brain in Post-traumatic Stress

  • study on Post-traumatic Stress
  • open to healthy males ages 21-65

• Women Informed to Screen Depending on Measures of Risk (Wisdom Study)

  • study on Breast Cancer and Cancer, General
  • open to healthy females ages 40-74

• YourMove Study: Optimizing Individualized and Adaptive mHealth Interventions Via Control Systems Engineering Methods

  • study on Physical Inactivity and Sedentary Behavior
  • open to healthy people ages 25-80

Last updated September 27, 2023