for people ages 18 years and up (full criteria)
Healthy Volunteers
healthy people welcome
at La Jolla, California
study started
completion around
Principal Investigator
by Gregory Aarons
Headshot of Gregory Aarons
Gregory Aarons



This project will test an implementation strategy that seeks to align system, organization, and clinic leadership strategies to implement and sustain the Lyssn artificial intelligence (AI) quality assurance platform to support implementation of Motivational Interviewing (MI) and evidence-based practice (EBP) for substance use disorders. The Leadership and Organizational Change for Implementation - System Level (LOCI-SL) strategy seeks to engage policymakers and funders at the system level to improve implementation leadership, climate, provider attitudes and behaviors at the provider organization level to enhance implementation climate for EBP. LOCI-SL will be tested in a statewide addiction service system through clinics in community based behavioral health organizations.

Official Title

Statewide System and Organizational Strategy for Evidence-Based Practice Implementation and Sustainment in Substance Use Disorder Treatment


The NIH has called for testing promising implementation strategies (PAR-19-274) and there is a critical need for implementation and sustainment of effective and evidence-based practices (EBPs) to address health conditions including substance use disorders (SUDs) which are among the most complex of public health issues. The proposed project is consistent with NIDA's Priority Focus Area "Strategies to improve the effective and sustainable implementation of evidence-based prevention and treatment interventions (implementation science)." Most implementation strategies do not address the complex multilevel context for implementation in public service sectors, but rather focus on direct service providers. This proposed project will expand the Leadership and Organizational Change for Implementation (LOCI) organizational change strategy for EBP implementation and sustainment, to address the larger outer system context in which SUD treatment organizations operate through engaging state policy and funding stakeholders along with community-based behavioral health agencies to understand and work toward aligning state-level policies and with organizational implementation improvement strategies. The project will focus on implementation and sustainment of the Lyssn artificial intelligence (AI) quality assurance platform along with implementation of Motivational Interviewing (MI). Consistent with the Exploration, Preparation, Implementation, Sustainment (EPIS) framework and system and organizational theory, the investigators will add a system level component to LOCI with the goal of bridging outer and inner context and developing and aligning a positive implementation climate to support implementation and sustainment of Lyssn and MI in SUD treatment agencies. The study will use mixed qualitative and quantitative methods in a stepped-wedge design to examine change in implementation leadership and implementation climate as a function the LOCI-SL intervention as well as exploring subsequent Lyssn and MI sustainment. The study will also include a "scaling-out" aim in which data from this study will be used to compare proposed mediational pathways (i.e., mechanisms) with data from a prior study. The study will involve ongoing engagement with state policy and funding stakeholders and qualitative examination of ways to facilitate academic-policy collaborations to enhance EBP implementation and sustainment.


Control, Experimental, Leadership and Organizational Change for Implementation, LOCI


For people ages 18 years and up

  1. Stakeholders from Oregon Health Authority (OHA), Oregon Alcohol and Drug Policy Commission (ADPC), staff at provider/payer advocacy organizations (e.g., CCO Oregon, Oregon Council for Behavioral Health), and relevant managed care organizations (Coordinated Care Organizations, CCOs), Indiana Department of Mental Health and Addiction (DMHA), or Indiana Department of Child Services (DCS).
  2. Executives and/or managers at participating substance use disorder and/or mental health treatment agencies.
  3. Clinic managers/supervisors in clinics that provide substance use disorder and/or mental health treatment.
  4. Counselors (i.e., service providers) employed at participating agencies that provide substance use disorder and/or mental health treatment.


  • UC San Diego accepting new patients
    La Jolla California 92093 United States

Lead Scientist at UCSD

  • Gregory Aarons
    Dr. Aarons is clinical and organizational psychologist, is a Professor in the Department of Psychiatry at the University of California, San Diego (UCSD), a faculty member in the UCSD/SDSU Joint Doctoral Program in Clinical Psychology, Director of the Child and Adolescent Services Research Center (CASRC) and Co-Director of the Center for Organizational Research on Implementatio…


accepting new patients
Start Date
Completion Date
University of California, San Diego
Study Type
Expecting 364 study participants
Last Updated