Acute Respiratory Distress Syndrome clinical trials at UCSD
3 in progress, 2 open to eligible people
Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome
open to eligible people ages 18 years and up
The goal of this interventional study is to compare standard mechanical ventilation to a lung-stress oriented ventilation strategy in patients with Acute Respiratory Distress Syndrome (ARDS). Participants will be ventilated according to one of two different strategies. The main question the study hopes to answer is whether the personalized ventilation strategy helps improve survival.
La Jolla, California and other locations
STimulation to Activate RespIration
open to eligible people ages 18 years and up
Multi-center, randomized, controlled, open-label Phase 2 feasibility trial. Subjects on mechanical ventilation (MV) for acute hypoxemic respiratory failure (AHRF) with lung injury (including subjects who meet criteria for acute respiratory distress syndrome (ARDS)) will be randomized 2:1 to diaphragm neurostimulation-assisted ventilation (DNAV) using the AeroNova System plus lung-protective ventilation (Treatment) vs. lung-protective ventilation alone (Control).
La Jolla, California and other locations
Personalized Ventilator Settings for Patients on ECMO
Sorry, not yet accepting patients
While mechanical ventilation can be used to sustain life in those with lung injury, it, can further worsen lung injury or prevent lung healing resulting in high morbidity and mortality as seen in Acute Respiratory Distress Syndrome (ARDS). Using extracorporeal membrane oxygenation (ECMO), the highest level of life support also known as the heart-lung machine, investigators may minimize injury from mechanical ventilation to allow the lungs to heal; however, the optimal ventilator strategies while on ECMO are unknown. This study will evaluate personalized ventilator strategy compared to standard of care ventilation.
La Jolla, California
Our lead scientists for Acute Respiratory Distress Syndrome research studies include Mazen F Odish, M.D. Kenneth Chen, MD.
Last updated: