Summary

for people ages 18 years and up (full criteria)
at San Diego, California
study started
estimated completion:
Edward Cachay

Description

Summary

A retrospective and prospective study among people living with HIV (PLWH) that assesses hepatitis C (HCV) treatment uptake during periods before and after direct acting antivirals (DAA) introduction, and its impact on the HCV epidemic among PLWH.

Official Title

Impact of Direct Acting Antivirals Uptake in Controlling Hepatitis C Epidemic and Modeling Interventions for Hepatitis C Elimination Among HIV-infected Persons in San Diego

Details

A study that aims to quantify the state of DAA uptake and its impact on the HCV epidemic among PLWH in San Diego, and to characterize negative predictors of DAA treatment uptake among PLWH in San Diego. Retrospective and prospective data from UCSD Owen Clinic will be utilized to calculate HCV prevalence, primary incidence, and reinfection incidence. Using mathematical epidemic models, the study will assess levels of existing and scaled-up interventions necessary for HCV elimination from PLWH in San Diego.

Keywords

Hepatitis C Hepatitis C, Chronic HIV/AIDS HIV Direct acting antivirals Hepatitis C modeling Hepatitis Hepatitis A Retrospective Prospective

Eligibility

You can join if…

Open to people ages 18 years and up

  • Any adult (≥ 18 years) HIV-infected patient attending the UCSD Owen Clinic
  • With history of acute or chronic HCV infection defined as having a detectable HCV viral load with or without a positive HCV antibody

You CAN'T join if...

  • With no history of or current HCV infection defined as having a negative HCV antibody from 2008 to 2020

Location

  • Owen Clinic-University of California, San Diego accepting new patients
    San Diego California 92103-8186 United States

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, San Diego
ID
NCT03551002
Lead Scientist
Edward Cachay
Study Type
Observational
Last Updated