for people ages 18 years and up (full criteria)
at San Diego, California
study started
estimated completion
Principal Investigator
by Edward Cachay, MD, MAS
Headshot of Edward Cachay
Edward Cachay



A retrospective and prospective study among people living with HIV (PLWH) that assesses hepatitis C (HCV) treatment uptake during periods before and after direct acting antivirals (DAA) introduction, and its impact on the HCV epidemic among PLWH.

Official Title

Impact of Direct Acting Antivirals Uptake in Controlling Hepatitis C Epidemic and Modeling Interventions for Hepatitis C Elimination Among HIV-infected Persons in San Diego


A study that aims to quantify the state of DAA uptake and its impact on the HCV epidemic among PLWH in San Diego, and to characterize negative predictors of DAA treatment uptake among PLWH in San Diego. Retrospective and prospective data from UCSD Owen Clinic will be utilized to calculate HCV prevalence, primary incidence, and reinfection incidence. Using mathematical epidemic models, the study will assess levels of existing and scaled-up interventions necessary for HCV elimination from PLWH in San Diego.


Hepatitis C, Hepatitis C, Chronic, HIV/AIDS, HIV, Direct acting antivirals, Hepatitis C modeling, Hepatitis A, Chronic Hepatitis C, Hepatitis, Retrospective, Prospective


You can join if…

Open to people ages 18 years and up

  • Any adult (≥ 18 years) HIV-infected patient attending the UCSD Owen Clinic
  • With history of acute or chronic HCV infection defined as having a detectable HCV viral load with or without a positive HCV antibody

You CAN'T join if...

  • With no history of or current HCV infection defined as having a negative HCV antibody from 2008 to 2020


  • Owen Clinic-University of California, San Diego accepting new patients
    San Diego California 92103-8186 United States

Lead Scientist at UCSD

  • Edward Cachay, MD, MAS
    I joined the University of California, San Diego in the Owen Clinic in 2007, having completed a fellowship in Infectious Diseases and a Master in Advanced Studies. During this time I have dedicated my professional time as a clinical teacher whose scholarly portfolio emphasized the management of HIV and its associated co-morbidities.


accepting new patients
Start Date
Completion Date
University of California, San Diego
Study Type
Expecting 450 study participants
Last Updated