for people ages 19 years and up (full criteria)
at San Diego, California and other locations
study started
completion around



The purpose of this registry study is to actively monitor people with GGOs and collect information about them, so that investigators can learn more about these lesions and about the risk of developing lung cancer in study participants whose GGOs are being monitored in the active surveillance program.

Official Title

Thoracic Surgery Oncology Group (TSOG) Protocol: Registry Trial of Active Surveillance for Multifocal Ground Glass Opacities (GGOs)


Multiple Ground Glass Opacities (GGOs)


You can join if…

Open to people ages 19 years and up

  • Age greater than 18 years
  • Have two or more GGOs on initial CT imaging
  • GGOs must be measure ≤3.0 cm and ≥0.6 cm in the greatest dimension
  • GGOs must be greater than half ground glass

    A biopsy is not necessary for inclusion in the trial. Biopsy of a GGO, even with a diagnosis of adenocarcinoma, does not necessarily preclude enrollment in this surveillance protocol. In other words, patients with a diagnosis of adenocarcinoma are still eligible, at the discretion of the clinician and/or investigator, if they meet the above criteria.

You CAN'T join if...

  • Patients who are actively undergoing lung cancer treatment or have a history of lung cancer, except for cases of completely resected pathologic stage IA nonsmall cell lung cancer (NSCLC). Patients with stage IA NSCLC and multiple GGOs can enroll in this active surveillance protocol after complete resection of the NSCLC and confirmation of stage on final pathologic assessment.
  • The presence of any solid lesion ≥0.6 cm suspicious for malignancy.
  • Patients who are actively undergoing treatment for other malignancies


  • University of California San Diego
    San Diego California 92103 United States
  • Stanford University Medical Center (Data collection only)
    Stanford California 94305-5408 United States


in progress, not accepting new patients
Start Date
Completion Date
Memorial Sloan Kettering Cancer Center
Memorial Sloan Kettering Cancer Center
Study Type
Observational [Patient Registry]
About 338 people participating
Last Updated