for people ages 41 years and up (full criteria)
at San Diego, California
study started
estimated completion
Principal Investigator
Dawn M. Schiehser, PhD
Photo of Dawn M. Schiehser
Dawn M. Schiehser



To investigate the efficacy of Mindfulness-based Stress Reduction (MBSR),to improve HRQoL, cognition, and mood, as well as to determine the longevity of the treatment response in individuals with Parkinson's disease (PD).


Eligible study participants will be randomly assigned to one of two interventions: 1) Mindfulness Based Stress Reduction for Parkinson's disease; MBSR-PD or 2) Psychoeducational/supportive care. Interventions are held within a group format consisting of approximately 6-8 individuals with PD. Groups will meet once per week for over a 8-week period. All participants will be administered a battery of neuropsychological tests to measure HRQoL, cognition (e.g., executive function, attention, memory), and mood (i.e., anxiety, depression, and apathy), as well as motor symptoms, disease severity, and mindfulness engagement/practice. Tests will be administered at baseline, 8 weeks (post-treatment), and 6- and 12-months (follow-up assessments) by an examiner blinded to group assignment.


Parkinson's Disease Mindfulness Based Stress Reduction Quality of Life Mindfulness Intervention Parkinson Disease Psychoeducational/supportive care


You can join if…

Open to people ages 41 years and up

  1. Clinical diagnosis of PD based on UK Brain Bank Criteria
  2. >40 years of age
  3. Hoehn and Yahr Rating Scale (HYRS) <5

You CAN'T join if...

  1. Secondary causes of Parkinsonism (e.g. corticobasal degeneration, progressive supranuclear palsy, drug-induced parkinsonism)
  2. Other neurological conditions (e.g. stroke)
  3. Clinical diagnosis of dementia based on any previous neuropsychological testing
  4. Psychosis, antipsychotic treatment or treatment for substance abuse
  5. Uncorrected vision or hearing to adequately participate in the intervention
  6. Modified HYRS >4 (i.e. wheel chair bound or bedridden unless aided)
  7. Prior formal training in MBSR or regular current MBSR practice
  8. Active/current participation in a psychological/behavioral treatment, such as Cognitive Behavioral Therapy (CBT)
  9. Active/current suicidal ideation


  • VA San Diego Healthcare System, San Diego, CA
    San Diego California 92161 United States

Lead Scientist at UCSD

  • Dawn M. Schiehser, PhD
    Biography Dr. Schiehser received her Ph.D. in Clinical Psychology with a specialization in Neuropsychology from Drexel University. She completed a pre-doctoral Clinical Psychology (Neuropsychology specialization) internship at Tulane University School of Medicine and a National Institutes of Health Postdoctoral Fellowship at UCSD.


in progress, not accepting new patients
Start Date
Completion Date
VA Office of Research and Development
Study Type
Last Updated