for people ages 18-90 (full criteria)
at La Jolla, California
study started
estimated completion
Principal Investigator
by Claude B Sirlin, MD
Photo of Claude B Sirlin
Claude B Sirlin



This pilot study will evaluate conventional and investigational MR imaging and spectroscopic sequences and collect data to help plan more definitive future studies.


This prospective pilot study evaluates the comparative and additive diagnostic performance of Magnetic Resonance Elastography (MRE) and corrected-T1 (cT1) for the detection and staging of fibrosis and inflammation in Nonalcoholic Steatohepatitis (NASH), using histology as the reference standard.


Nonalcoholic Fatty Liver Nonalcoholic Steatohepatitis Liver Fibroses Liver Inflammation Fatty Liver Non-alcoholic Fatty Liver Disease Liver Cirrhosis Hepatitis Fibrosis Inflammation


You can join if…

Open to people ages 18-90

  • Adult subjects of any gender and any ethnic group with known or suspected NASH
  • Subject is willing and able to complete required research procedures (screening/enrollment, clinical evaluation, safety procedures, and research MRI exam), and is willing to allow the study team to review clinical data including but not limited to other clinical radiology reports and images and clinical or research biopsy results
  • Subject has been fully informed and has personally signed and dated the written Informed Consent and Health Insurance Portability and Accountability Act (HIPAA) documents
  • Subject has had or is expected to have a clinical or research biopsy within 150 days of the MR exam

You CAN'T join if...

  • VA subject
  • < 18 years of age
  • Subject does not have a physician and does not wish to be contacted about possible incidental findings
  • MRI contraindication(s)
  • Subject knows that she is pregnant or states she is trying to become pregnant


  • University of California, San Diego accepting new patients
    La Jolla California 92037 United States

Lead Scientist at UCSD

  • Claude B Sirlin, MD
    Professor, Radiology. Authored (or co-authored) 381 research publications.


accepting new patients
Start Date
Completion Date
University of California, San Diego
Study Type
Last Updated