for people ages 18 years and up (full criteria)
Healthy Volunteers
healthy people welcome
at San Diego, California
study started
completion around
Principal Investigator
by Sheng Xu, PhD



The main objective of this research is to measure the Doppler signal by the ultrasonic patch. Blood flow measurement is critical for vasospasm, stroke, and embolism monitoring on patients in the ICU or understanding the neurovascular coupling on different subjects. Currently, A conventional transcranial Doppler (TCD) probe is widely used for these applications. A headset design must be applied and fixed on the participants to obtain stable blood flow spectra. However, the TCD headset is operator dependent. The operator needs to be a trained expert and hold the ultrasound probe to get accurate blood flow velocity information. The stretchable and wearable non-invasive ultrasonic patch can not only free the operator's hands but can also provide long-term continuous monitoring, which is not possible by using the current operator-dependent ultrasound machine. The device can be conformal to the skin and attached to the skin surface.

Official Title

Non-invasive Monitoring of Blood Flow in the Brain by Using a Wearable Ultrasound Patch


Medical Device Complication, Brain Injuries, Brain Diseases, Stroke, Vasospasm, Blood flow monitoring in the brain


You can join if…

Open to people ages 18 years and up

  • Able to provide informed consent.
  • In relatively good health with no serious medical conditions.

You CAN'T join if...

  • Inability to sign the informed consent.
  • History of the following conditions: Heart attack, low blood pressure, aortic stenosis/carotid artery stenosis (also known as heart valve disease), glaucoma (a group of eye conditions that damage the optic nerve) or retinopathy (a disease of the eye retina).


  • Structural and Materials Engineering (SME) building Room 310 accepting new patients
    San Diego California 92122 United States

Lead Scientist at UCSD

  • Sheng Xu, PhD
    Associate Professor, Nanoengineering, Vc-academic Affairs. Authored (or co-authored) 24 research publications


accepting new patients
Start Date
Completion Date
University of California, San Diego
Study Type
Expecting 60 study participants
Last Updated