This study is accepting new patients by invitation only

Ventilator Mode and Respiratory Physiology

a study on Pulmonary Disease Respiratory Failure Respiratory Effort Breathing Mechanics

Summary

Eligibility
for people ages 18 years and up (full criteria)
Location
at La Jolla, California
Dates
study started
completion around
Principal Investigator
by Alex Pearce, MD

Description

Summary

Modern intensive care units (ICUs) are increasingly adopting newer modes of mechanical ventilation such as adaptive pressure control (APC) modes but there are limited data available regarding risks and benefits of newer modes versus traditional ventilation modes. APC can inadvertently deliver high tidal volumes, which maybe harmful. High tidal volumes may be unrecognized by the provider, due to the complexities of ventilator algorithms and patient interactions. The objective of this aim is to identify risk factors for excess tidal volumes in patients on adaptive pressure control.

Keywords

Pulmonary Disease, Respiratory Failure, Respiratory Effort, Breathing Mechanics, Respiratory Insufficiency, lung mechanics, respiratory drive and effort

Eligibility

You can join if…

Open to people ages 18 years and up

  • Admitted to ICU with acute respiratory failure
  • On adaptive pressure control mode of ventilation
  • Tidal volumes set between 5-8 cc/kg ideal body weight

You CAN'T join if...

  • Current use of neuromuscular blockade
  • Inability to obtain consent from patient or surrogate decision maker
  • Treating clinician refusal

Location

  • University of California San Diego Health
    La Jolla California 92037 United States

Lead Scientist at UCSD

  • Alex Pearce, MD
    Associate Physician Diplomate, Medicine, Vc-health Sciences-schools. Authored (or co-authored) 18 research publications

Details

Status
accepting new patients by invitation only
Start Date
Completion Date
(estimated)
Sponsor
University of California, San Diego
ID
NCT06624254
Study Type
Observational
Participants
Expecting 60 study participants
Last Updated