Concussion clinical trials at UCSD
3 in progress, 1 open to eligible people
Combined Neuromodulation and Cognitive Training for Post-mTBI Depression
open to eligible people ages 18-65
The primary goal of this clinical trial is to evaluate whether Personalized Augmented Cognitive Training (PACT) plus intermittent theta burst stimulation (iTBS) is effective for treating depression in Service Members, Veterans, and civilians who have sustained a mild TBI. Participants will receive PACT plus 20 sessions of iTBS or sham iTBS over 4 weeks. Assessments will occur at baseline, 2 weeks, 4 weeks, and 8 weeks. Researchers will compare the PACT+iTBS group to the PACT+sham iTBS group to see if PACT+iTBS is associated with more depression improvement.
La Jolla, California
Retraining Neural Pathways Improves Cognitive Skills After A Mild Traumatic Brain Injury
Sorry, in progress, not accepting new patients
The proposed study tests the efficacy (Phase II) of 36 30-minute training sessions of PATH neurotraining followed by digit memory exercises to improve working memory, processing speed and attention in mTBI patients rapidly and effectively to provide clinical testing of a therapeutic training for the remediation of cognitive disorders caused by a concussion. This study will contribute to the fundamental knowledge of how to remediate concussions from a mTBI to enhance the health, lengthen the life and reduce the disabilities that result from a mTBI.
San Diego, California and other locations
SMART-CPT for PTSD/Concussion Implementation
Sorry, accepting new patients by invitation only
The clinical implementation trial will evaluate effectiveness and feasibility, acceptability, appropriateness, barriers, and facilitators of implementing SMART-CPT, a treatment targeting the two primary factors leading to poor outcomes following concussion, in Veterans. It will test effectiveness and broad implementation feasibility of SMART-CPT compared to standard Cognitive Processing Therapy (CPT).
San Diego, California
Our lead scientists for Concussion research studies include Elizabeth Twamley, PhD Amy Jak.
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