Knee Replacement clinical trials at UCSD
3 in progress, 2 open to eligible people
iPACK Block With Dexamethasone For Total Knee Replacement
open to eligible people ages 18 years and up
Comparing the pain control outcomes for patients undergoing total knee arthroplasty (TKA) with either: 1) adductor canal single shot injection plus placebo iPACK injection or 2) adductor canal single shot injection plus bupivacaine and dexamethasone iPACK injection. There are two surgical approaches for TKA 1) open 2) ROSA robotic assisted. Both follow the same pain management pathway. We plan to enroll patient undergoing either surgical procedure.
San Diego, California
Treatment of Post-Operative Pain Following Orthopedic Surgery With SPRINT® Peripheral Nerve Stimulation (PNS) System
open to eligible people ages 21 years and up
The purpose of this study is to gather information about how knee pain changes when small amounts of electricity are delivered to the nerves in the leg. This study will involve the use of a Peripheral Nerve Stimulation (PNS) System that is made by SPR Therapeutics (the sponsor of the study). The SPRINT PNS System was cleared by the FDA for up to 60 days of use in the back and/or extremities for the management of acute and chronic pain.
San Diego, California and other locations
A Multicenter Study to Evaluate Functional Outcome After Knee Replacement
Sorry, in progress, not accepting new patients
Patients will be consecutively enrolled by implant. Implant groups will be those who have undergone surgery with either a ConforMIS iTotal® CR TKA or an Off-the- Shelf (OTS) system. The patient will conduct functional testing and answer questionnaires. The results will compare the ConforMIS iTotal with an Off the Shelf Knee replacement.
La Jolla, California and other locations
Our lead scientists for Knee Replacement research studies include Engy Said, MD Brian M. Ilfeld, MD, MS.
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