Skip to main content

Osteoarthritis clinical trials at UCSD

8 in progress, 2 open to eligible people

Showing trials for
  • A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis Pain

    open to eligible people ages 18-90

    There is an urgent public health need to reduce reliance on opioids for effective long-term pain management, particularly in knee osteoarthritis (KOA). This effectiveness trial will compare commonly recommended treatments to reduce pain and functional limitations in KOA.These results will lead to improved patient selection for treatment and inform evidence based guidelines by offering well-tested, effective, non-surgical alternatives.

    San Diego, California and other locations

  • Bone Marrow Aspirate Concentrate (BMAC)Treatment for Knee Osteoarthritis

    open to eligible people ages 45-75

    The purpose of this study is to investigate the safety and effectiveness of bone marrow aspirate concentrate (BMAC) in patients with moderate to severe osteoarthritis of the knee. BMAC provides a rich source of mesenchymal stem cells (MSCs) and is a stem cell-based therapy that has been reported to preserve or improve the structure of joints. The Angel System is the device used in this study to concentrate bone marrow from the patient and is intended to separate a mixture of blood and bone marrow and collect plasma rich platelets preoperative to a surgical procedure. The goal of this study is to identify whether BMAC can be an effective and safe treatment for patients with osteoarthritis of the knee.

    La Jolla, California

  • A Multicenter Study to Evaluate Functional Outcome After Knee Replacement

    Sorry, in progress, not accepting new patients

    Patients will be consecutively enrolled by implant. Implant groups will be those who have undergone surgery with either a ConforMIS iTotal® CR TKA or an Off-the- Shelf (OTS) system. The patient will conduct functional testing and answer questionnaires. The results will compare the ConforMIS iTotal with an Off the Shelf Knee replacement.

    La Jolla, California and other locations

  • A Pilot Trial to Assess Low-Intensity Ultrasound in Osteoarthritis

    Sorry, in progress, not accepting new patients

    The purpose of this exploratory trial is to investigate whether PLIUS is potentially effective as a disease and symptom modifying intervention in patients with early knee OA.

    San Diego, California and other locations

  • Effect of Anti-inflammatory (ITIS) Diet in Rheumatoid Arthritis

    Sorry, in progress, not accepting new patients

    to study the effect of anti-inflammatory diet on clinical and biological outcomes in rheumatoid arthritis

    La Jolla, California

  • iPACK Block With Dexamethasone For Total Knee Replacement

    Sorry, not yet accepting patients

    Comparing the pain control outcomes for patients undergoing total knee arthroplasty (TKA) with either: 1) adductor canal single shot injection plus placebo iPACK injection or 2) adductor canal single shot injection plus bupivacaine and dexamethasone iPACK injection. There are two surgical approaches for TKA 1) open 2) ROSA robotic assisted. Both follow the same pain management pathway. We plan to enroll patient undergoing either surgical procedure.

  • Prospective Clinical Follow-up of the Echo Bi-Metric Microplasty Stem for Total Hip Arthroplasty

    Sorry, in progress, not accepting new patients

    The primary objective of this study is to characterize survivorship of the Echo Bi-Metric Microplasty stem in unilateral or bilateral primary total hip arthroplasty at 5 years postoperative.

    San Diego, California and other locations

  • Safety and Effectiveness of Cartiva Implant in the Treatment of First CMC Joint Osteoarthritis Compared to LRTI (GRIP 2)

    Sorry, in progress, not accepting new patients

    This study will evaluate whether Cartiva is an effective treatment for individuals with osteoarthritis of the first CMC joint in the hand compared to LRTI.

    San Diego, California and other locations

Last updated: