Summary

Eligibility
for females (full criteria)
Location
at La Jolla, California
Dates
study started
completion around
Principal Investigator
by Christina Chambers, PhD, MPH

Description

Summary

The purpose of the OTIS Autoimmune Diseases in Pregnancy Study is to monitor planned and unplanned pregnancies exposed to certain medications, to evaluate the possible teratogenic effect of these medications and to follow live born infants for one year after birth. With respect to fetal outcome, it is important to evaluate the spectrum of outcomes that may be relevant to a medication exposure during pregnancy, and these include both easily recognizable defects which are visible at birth, as well as more subtle or delayed defects that may not be readily identifiable without special expertise and observation beyond the newborn period.

Official Title

Stelara® and Tremfya® Pregnancy Exposure Registry: OTIS Autoimmune Diseases in Pregnancy Project

Details

The purpose of the Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project is to follow pregnant women or women who have delivered a baby, who have been treated with Stelara or Tremfya within 3 months of their last menstrual period (LMP) or during pregnancy to evaluate the possible effect of this medication on the pregnancy outcome including child development and growth up to one year of age.

Keywords

Psoriasis, Pregnancy, Psoriatic Arthritis, Crohn Disease, autoimmune disease, Stelara, ustekinumab, birth outcome, malformation, birth defect, Crohn's Disease, Tremfya, guselkumab, Arthritis, Autoimmune Diseases, Stelara (ustekinumab) exposed, Tremfya (guselkumab) exposed

Eligibility

You can join if…

Open to females

  • Documentation of an exposure to Stelara (ustekinumab) or Tremfya (guselkumab) during pregnancy or within 3 months prior to the first day of the last menstrual period (LMP) for any number of days, at any time, at any dose, and at any time until completion of pregnancy.
  • Documentation of gestational timing of the exposure to Stelara (ustekinumab) or Tremfya (guselkumab)

You CAN'T join if...

  • Women who have not have an exposure to Stelara (ustekinumab) or Tremfya (guselkumab) during pregnancy or within 3 months of the first day of the last menstrual period.

Location

  • University of California, San Diego accepting new patients
    La Jolla California 92093 United States

Lead Scientist at UCSD

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, San Diego
Links
Official research website of the Organization of Teratology Information Specialists, Studies coordinated at the University of California, San Diego
ID
NCT02103361
Study Type
Observational [Patient Registry]
Participants
Expecting 200 study participants
Last Updated