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Osteoarthritis clinical trials at UCSD

6 in progress, 4 open to eligible people

Showing trials for
  • Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis Pain

    open to eligible people ages 18 years and up

    There is an urgent public health need to reduce reliance on opioids for effective long-term pain management, particularly in knee osteoarthritis (KOA). This effectiveness trial will compare commonly recommended treatments to reduce pain and functional limitations in KOA.These results will lead to improved patient selection for treatment and inform evidence based guidelines by offering well-tested, effective, non-surgical alternatives.

    San Diego, California and other locations

  • Anti-inflammatory (ITIS) Diet in Knee Osteoarthritis

    open to eligible people ages 18 years and up

    To study the effect of anti-inflammatory diet on clinical and biological outcomes in patients with knee osteoarthritis

    La Jolla, California

  • Anti-inflammatory Diet in Osteoarthritis

    open to eligible people ages 18 years and up

    In a previous exploratory study, the investigators observed an effect on disease activity outcomes of anti-inflammatory diet. The investigators also observed change in microbiome and circulating metabolites. The current study will determine whether or not the addition of anti-inflammatory diet improves the clinical outcomes in participants with Osteoarthritis, and the role of microbiome and circulating metabolites.

    San Diego, California

  • Pharmacodynamics of GNSC-001 Intra-articular Injection for Knee Osteoarthritis

    open to eligible people ages 40-75

    The goal of this clinical study is to determine if a single injection of 1 or more dose levels of adeno-associated virus (AAV) gene therapy (GNSC-001) is safe and tolerated compared to placebo in participants with painful osteoarthritis (OA) of the knee.

    San Diego, California and other locations

  • CNTX-6970 in Subjects With Knee Osteoarthritis Pain.

    Sorry, in progress, not accepting new patients

    The primary objective of this study is to evaluate the safety and efficacy of CNTX-6970 for the treatment of pain related to OA of the knee compared to placebo. CNTX-6970 is being developed as a new treatment for chronic pain, including painful osteoarthritis of the knee.

    La Jolla, California and other locations

  • Clinical Follow-up of the Echo Bi-Metric Microplasty Stem for Total Hip Arthroplasty

    Sorry, in progress, not accepting new patients

    The primary objective of this study is to characterize survivorship of the Echo Bi-Metric Microplasty stem in unilateral or bilateral primary total hip arthroplasty at 5 years postoperative.

    San Diego, California and other locations

Our lead scientists for Osteoarthritis research studies include .

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