for people ages 18-80 (full criteria)
at La Jolla, California and other locations
study started
completion around



Objectives: To identify a candidate set of biomarkers specific to AxPsA. Overview: Clinical and imaging characterization of PsA patients will be combined with extensive molecular assessment of both liquid and tissue compartments to identify biomarkers which differentiate PsA patients with and without axial involvement


Psoriatic Arthritis, Arthritis


You can join if…

Open to people ages 18-80

  • Persons with PsA diagnosed by a consultant Rheumatologist with disease duration of > 3 months but < 10 years with or without IBP.
    • Adults between the ages 18 and 80 years, with joint disease onset after 16 years of age
    • Patients able to understand and complete consent procedures
    • Study participants must have PsA, meet CASPAR criteria, and must have active disease as defined by the treating rheumatologist, including an evaluable psoriatic skin lesion amenable to 6mm punch skin biopsy.

      o Psoriasis should be diagnosed by a consultant rheumatologist or dermatologist.

    • Study participants must have been on consistent therapy for their PsA for the past 90 days
    • Study participants must be naïve to biological treatment and targeted synthetic

      DMARD treatment (examples: JAK inhibitors, apremilast)

You CAN'T join if...

  • • Persons with musculoskeletal (peripheral or axial) symptoms for >10 years
    • Persons with planned major surgery (e.g., joint replacement) within the duration of the collection of data for the study
    • Persons with a history of chemotherapy, radiation therapy or immunotherapy for cancer in the preceding 5 years.
    • Persons with ongoing cancer (not excluding non-melanoma skin, cervical/breast in-situ carcinoma) but those fully recovered from an episode of cancer (in remission for more than 5 years) may be included at the discretion of the patient's treating rheumatologist.
    • Persons with an active severe or serious infection
    • Patients with non-severe infection at the discretion of the Investigator
    • Persons with other concomitant disorders incompatible with study (at discretion of Investigator).


  • University of California San Diego
    La Jolla California 92093 United States
  • Seattle Rheumatology Associates
    Seattle Washington 98122 United States


accepting new patients by invitation only
Start Date
Completion Date
Group for Research and Assessment of Psoriasis and Psoriatic Arthritis
Study Type
Expecting 40 study participants
Last Updated