for people ages 60-80 (full criteria)
healthy people welcome
at La Jolla, California
study started
estimated completion:
Amy Jak



Vast evidence supports use of physical exercise and cognitive stimulation for lowering risk for cognitive decline and dementia, with combinations of non-pharmacological interventions providing greatest promise for impacting cognitive aging. This, paired with limited cognitive benefits from pharmacological interventions in dementia, has shifted focus to non-pharmacological interventions administered earlier in the disease course. This application, therefore, proposes a randomized controlled trial (RCT; 12-week active intervention, 3- and 6-month follow-up) comparing 3 conditions: walking program (guided progressive increases in weekly step counts), computer-based cognitive training program (Brain HQ, Posit Science), and combination of the exercise and cognitive program, on cognitive, functional, and diagnostic outcomes in 60 sedentary, community-dwelling adults with mild cognitive impairment (MCI).


Mild Cognitive Impairment Cognitive Dysfunction Walking Intervention Cognitive Training Intervention Combined Intervention


You can join if…

Open to people ages 60-80

  • MCI diagnosis (can be self referral, will determine eligibility at baseline)

You CAN'T join if...

  • Dementia diagnosis
  • Head trauma
  • Neuro/psychiatric disorders
  • Current substance dependence
  • Sensory/mobility deficits
  • No more than 1 hour of purposeful, aerobic activity/week
  • Currently engaging in any other brain-stimulating computer program (No more than 1 hour a week)


  • UCSD accepting new patients
    La Jolla California 92037 United States


accepting new patients
Start Date
Completion Date
University of California, San Diego
Lead Scientist
Amy Jak
Study Type
Last Updated
December 1, 2017