for people ages 18 years and up (full criteria)
at San Diego, California
study started
estimated completion
Principal Investigator
by Brook L Henry, Ph.D.



HIV is associated with a pattern of neurocognitive deficits, metabolic dysfunction, and an elevated risk for cardiovascular disease (CVD), phenomena that remain untreated despite the use of medications to control the disease. This proposal will examine the effect of a personalized, automated, interactive mobile phone text message intervention (iSTEP) designed to increase moderate physical activity (PA), decrease sedentary behavior (SB), and promote a healthy Mediterranean-style diet (MedDiet) in persons living with HIV (PLWH). The investigators propose that participants who receive the iSTEP intervention will increase the amount of physical activity, improve their diet, show a reduction in risk factors for CVD, and exhibit improved neurocognitive performance.


HIV/AIDS, physical activity, diet, mHealth, Fitbit, neurocognition, text messaging, Acquired Immunodeficiency Syndrome, HIV Infections, iSTEP


You can join if…

Open to people ages 18 years and up

  • ability to provide informed consent
  • HIV infection documented at the University of California, San Diego (UCSD) HIV Neurobehavioral Research Program (HNRP) or assessed by an HIV test at screening
  • proficient in English
  • physically capable of participating in moderate PA as screened by the Physical Activity Readiness Questionnaire
  • consent from primary care physician to participate in the study
  • able to consume walnuts - no nut allergies

You CAN'T join if...

  • any physical conditions that would prevent moderate physical activity or where moderate physical activity would represent a health risk for the individual, including a history of myocardial infarction or stroke
  • unwillingness or inability to participate in daily text messaging
  • tree nut allergy that would prevent walnut consumption or other food restrictions that would prevent participation in the Mediterranean-style diet intervention (e.g., unable to eat fish or use olive oil for cooking).


  • HIV Neurobehavioral Research Program accepting new patients
    San Diego California 92103 United States

Lead Scientist at UCSD

  • Brook L Henry, Ph.D.
    Assistant Researcher, Psychiatry, Vc-health Sciences-schools. Authored (or co-authored) 34 research publications


accepting new patients
Start Date
Completion Date
University of California, San Diego
Study Type
Expecting 150 study participants
Last Updated