for people ages 18 years and up (full criteria)
at La Jolla, California and other locations
study started
estimated completion



This study is an open label, long-term extension study for subjects with moderate to severe ulcerative colitis designed to evaluate long term therapy of CP-690,550.

Official Title

A Multi-center, Open-label Study Of Cp-690,550 In Subjects With Moderate To Severe Ulcerative Colitis


Ulcerative Colitis open-label long term treatment Colitis Ulcer Colitis, Ulcerative Tofacitinib CP-690,550 CP-690,550 5 mg BID CP-690,550 10 mg BID


You can join if…

Open to people ages 18 years and up

  • Subjects who completed induction studies A3921094 or A3921095 and were classified as not meeting clinical response criteria; OR
  • Subjects who completed maintenance study A3921096 or who discontinued treatment early in Study A3921096 due to treatment failure.

You CAN'T join if...

  • Subjects who had a major protocol violation in Study A3921094, A3921095 or A3921096.
  • Presence of indeterminate colitis, microscopic colitis, ischemic colitis, infectious colitis, or clinical findings suggestive of Crohn's disease.
  • Subjects who have had surgery for ulcerative colitis or in the opinion of the investigator, are likely to require surgery for ulcerative colitis during the study period.


  • Perlman Medical Offices - UC San Diego Health System
    La Jolla California 92037 United States
  • UCSD Medical Center
    La Jolla California 92093 United States
  • Altman Clinical and Translational Research Institute
    La Jolla California 92037-0897 United States
  • Investigational Drug Service Pharmacy
    La Jolla California 92037 United States
  • Sharp Rees-Stealy Medical Group
    San Diego California 92123 United States
  • Clinical Applications Laboratories, Inc.
    San Diego California 92103 United States
  • San Diego Endoscopy Center
    San Diego California 92103 United States


in progress, not accepting new patients
Start Date
Completion Date
To obtain contact information for a study center near you, click here.
Phase 3
Study Type
Last Updated